Conzip may also be used for other conditions as determined by your healthcare provider.
Conzip works in the brain to change how your body feels and responds to pain.
Conzip is available in the following dosage forms that are taken by mouth.
Tramadol is also available as tablets and liquid that you swallow. See Tramadol and Qdolo for more information.
Conzip should be stored at room temperature, between 68 F to 77 F (20 C to 25 C). It can be exposed to temperatures between 59 F to 86 F (15 C to 30 C) for shorter periods of time, such as when transporting it.
The most common side effects of Conzip are listed below. Tell your healthcare provider if you have any of these side effects that bother you.
There may be other side effects of Conzip that are not listed here. Contact your healthcare provider if you think you are having a side effect of a medicine. In the U.S., you can report side effects to the FDA at www.fda.gov/medwatch or by calling 800-FDA-1088. In Canada, you can report side effects to Health Canada at www.health.gc.ca/medeffect or by calling 866-234-2345.
While less common, the most serious side effects of Conzip are described below, along with what to do if they happen.
Severe Allergic Reactions. Conzip may cause allergic reactions, which can be serious. Get emergency help right away if you have any of the following symptoms of a serious allergic reaction.
Risk of Misuse and Addiction. Misusing Conzip can lead to serious side effects like coma or death. Misuse means taking a medicine in a way other than how it was prescribed. Take Conzip exactly as prescribed. Tell your healthcare provider if you feel that Conzip is not working. Call your healthcare provider right away or go to the nearest emergency room if you have any of the following serious symptoms.
Breathing Problems. Conzip may cause slow or shallow breathing, especially if you have breathing problems from another condition or take other medicines that can slow your breathing. Tell your healthcare provider if you develop severe sleepiness or trouble breathing, especially when you start Conzip or when your dose is increased. Get emergency help right away if you have any of the following symptoms.
Increased Pain Sensitivity (Hyperalgesia). Conzip can cause an increased sensitivity to pain. It can cause things that normally cause pain to feel more painful than usual. Conzip can also cause allodynia. This happens when things that normally do not cause pain, such as wearing glasses or brushing your hair, become painful. If your pain increases, do not take extra doses of Conzip. This could cause you to overdose or develop other serious side effects. Call your healthcare provider right away if your pain increases, you feel more sensitive to pain, or if you develop pain in other areas of the body.
Serotonin Syndrome. Serotonin syndrome is when there is too much of a substance called serotonin in your body. Conzip can cause serotonin syndrome when it is taken alone or with other medicines that affect serotonin. This condition can be life-threatening. Get emergency help if you have any of the following symptoms of serotonin syndrome.
Seizures. Some people who have taken Conzip have reported having seizures. There are many different types of seizures and some of them are not easy to recognize. Get emergency help right away if you have any of the following signs that a seizure is happening or could happen.
Suicidal Thoughts and Actions. Conzip may cause suicidal thoughts or actions in a small number of people. If you are about to harm yourself, call 911 or call or text 988, the Suicide & Crisis Lifeline. Call your healthcare provider right away if you have any of the following symptoms.
Reduced Adrenal Function. Long-term use of Conzip can cause your body’s adrenal glands to stop making as much cortisol (the stress hormone). This is known as adrenal insufficiency. Adrenal insufficiency can get worse if your body is under stress because of fever, surgery, or trauma. Tell your healthcare provider if you have any of the following symptoms of adrenal insufficiency.
Low Blood Pressure (Hypotension). Conzip may cause low blood pressure. If you feel faint or dizzy, lie down. Tell your healthcare provider right away if you have any of the following symptoms of low blood pressure.
Sphincter of Oddi Spasm. The sphincter of Oddi is a muscular valve in your body that controls the flow of bile and digestive juices from the pancreas into the small intestine. When this valve spasms, it may feel like getting a tight muscle cramp, causing pain and blocking the flow of these juices, which can lead to discomfort and digestive problems. This is more likely to happen if you do not have a gallbladder. Get emergency medical help if you have new or worse stomach pain or pain in the upper right side of your stomach-area that travels to your back or shoulder, with or without nausea and vomiting.
Low Sodium Level (Hyponatremia). Conzip may cause low sodium levels. Call your healthcare provider if you have any of the following symptoms of a low sodium level.
Low Blood Sugar (Hypoglycemia). Conzip can cause low blood sugar, which can be serious and may lead to death. You may need to check your blood sugar more often if you have changes to your diet, exercise regimen, or medicines for diabetes. Call your healthcare provider right away if you have any of the following symptoms of hypoglycemia.
Severe Skin Reactions. Conzip can cause severe skin reactions called Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) that can lead to death if not treated. If you develop a rash, call your healthcare provider right away. Get emergency help right away if you have any of the following symptoms of SJS or TEN.
Allergies to Ingredients. People who are allergic to any of the following should not take Conzip.
Your pharmacist can tell you all of the ingredients in Conzip.
Drug Interactions. Conzip should not be taken while you are using certain other medicines. Before taking Conzip, tell your healthcare provider about any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using or have used recently. See the Interactions section for more details.
Children. Conzip should not be used in any child younger than 12 years of age or in a child younger than 18 years of age after a surgery to remove their tonsils or adenoids (tonsillectomy and/or adenoidectomy). Slow or shallow breathing that can lead to death may occur.
Gut Blockage. Conzip should not be used if you have a blockage of your gut (bowel obstruction) or a narrowing of the stomach or intestines. Conzip can make these conditions worse.
Slowed Gut Movement. Paralytic ileus is a type of ileus where your intestines are unable to move food through them. Conzip can make this condition worse.
Lung problems. Conzip should not be used if you have severe asthma, trouble breathing, or other lung problems. Conzip can make these conditions worse.
Do not take Conzip unless it has been prescribed to you by a healthcare provider. Take it as prescribed.
Do not share Conzip with other people, even if they have the same condition as you. It may harm them.
Keep Conzip out of the reach of children. Conzip is a controlled substance because it can be misused or lead to dependence. Store Conzip in a safe place to protect it from theft. It is illegal to sell or give away this medicine.
Do not stop taking Conzip without talking to your healthcare provider. Stopping Conzip too quickly can cause serious withdrawal effects. Call your healthcare provider right away if you have any of the following symptoms.
Conzip can affect your alertness or coordination. Do not drive or do other activities that require alertness or coordination until you know how Conzip affects you.
People who are 65 years and older can be at greater risk for some side effects from Conzip. Talk to your healthcare provider about your risks if you are in this age group.
Do not chew, cut, or crush Conzip. This can cause you to overdose and die.
Do not take Conzip on an “as needed” basis. Taking too much Conzip can lead to breathing problems, seizures, and death.
Dispose of expired, unwanted, or unused Conzip right away by taking your medicine to an authorized DEA-registered collector or drug take back program. If one is not available, you can mix medicine with dirt, coffee grounds, or cat litter, then place the mixture in a sealed plastic bag and throw the bag in the trash.
Long-term use of Conzip may affect your ability to become pregnant or get a partner pregnant. Talk with your healthcare provider if you have any concerns.
Tell your healthcare provider about all of your health conditions and any prescription or over-the-counter (OTC) medicines, vitamins/minerals, herbal products, and other supplements you are using. This will help them determine if Conzip is right for you.
In particular, make sure that you discuss any of the following.
Current and Past Health Conditions. Tell your healthcare provider if you have any of the following.
Pregnancy. Conzip may cause harm to an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. Your healthcare provider will advise you if you should take Conzip while you are pregnant or trying to get pregnant. If you take Conzip on a regular basis during pregnancy, your baby may have withdrawal symptoms that can be life-threatening. Tell your healthcare provider if you took Conzip during your pregnancy, especially near the end of your pregnancy.
Breastfeeding. Conzip passes into breast milk. Breastfeeding is not recommended while you are taking Conzip. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take Conzip while breastfeeding.
